OTP Center

Phentermine

All about phentermine

Phentermine is a weight loss medication that has been approved for long-term weight loss and weight management. It is often used in combination with topiramate. Phentermine is recommended for long-term use to both lose weight, and to maintain loss. It is an incredibly safe, non-addictive medication that has been used for over 50 years. FDA approved for three months’ worth of use at a time, Phentermine has proven to have a very high success rate when used properly.

How does phentermine work?

Phentermine works in your brain and nervous system, increasing the release of two neurotransmitters (dopamine and norepinephrine) in your brain to simulate metabolism and suppress hunger. Phentermine also works outside of the brain, triggering the release of adrenaline and epinephrine, hormones which have powerful fat-burning properties.

Paired with a dietary strategy, phentermine achieves significant weight loss. The medication doesn’t lose the weight for you — rather, it helps you not think about eating. The diet you select should work well with your personality, habits, and lifestyle. It’s also important to exercise regularly. Taking 37.5mg of phentermine daily for 12 weeks leads to an average weight loss of about 16 pounds.

Is phentermine right for you?

The only way to know for sure if phentermine is right for you is to schedule a consultation with our specialists at Genesis Lifestyle Medicine. During this consultation, your medical history will be taken, and a physical exam will be performed to determine if phentermine is a good option for your needs.


If you do begin phentermine, a follow-up appointment will be scheduled shortly after you begin taking it to ensure the medication is working well with your body. 


Our specialists will customize your phentermine dosage according to your specific needs and health. Many of our patients also take topiramate in conjunction with phentermine. Topiramate is an anticonvulsant and nerve pain medication.

Suppress your appetite

throughout the day

Phentermine is taken once a day, typically in the morning so that it can suppress your appetite from breakfast through dessert. Over the course of a few hours, the medication will rise in your bloodstream, reaching its peak concentration in 3 to 5 hours. After this, it will slowly decline over the rest of the day.

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